The Changing Trends Amongst Patients with Colorectal Carcinoma Presenting at Medical Oncology Department, JPMC

Authors

  • Sorath Bhutto Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.
  • Sana Hashmat Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.
  • Ghulam Haider Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.
  • Abdul Rehman Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.
  • Saima Zahoor Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.
  • Shayan Ali Qazi Senior lecturer, Sindh Institute of Urology and Transplantation
  • Areeba Qureshi Sindh Institute of Urology and Transplantation

DOI:

https://doi.org/10.38106/LMRJ.2024.6.4-03

Keywords:

colorectal cancer, oncology, adenocarcinoma, colon, rectum, neoplasm, Epidemiology

Abstract

Colorectal cancer (CRC) is the second leading cause of death This cross sectional study was conducted including biopsy proved adenocarcinoma of colon and rectum patients at outpatient unit of oncology department at Jinnah Post Graduate Medical College (JPMC), Karachi, Pakistan. The mean age of the patients was 40 years (IQR ± 16 years). Majority were males patients accounting for 66%. Majority reported to have frequent vegetable intake (89.8%) and comparably lower processed food intake (69.9%). 92% patients reported to have sedentary lifestyle, 58% were smokers, and 8% were alcohol abusers. Majority of patients (96.6%) had no family history of colorectal cancer. Rectal adenocarcinoma is identified in majority of patient between age 18-40 years (n 70; 65.4%, p=0.004) and this age group often present with Grade III (n=45; 83%,p<0.001) and Stage III of cancer ( n 58; 66.7%, p= <0.001). More patients of the age group of 18-40 years had poorly differentiated cancer (n 48; 44%, p<0.001). Few patients in this age group were smokers (n=47; 46%, p 0.005) and had history of alcoholic intake (n 5; 35%, p = 0.038). In our study population the age group 18 years to 40 years had considerably higher rate of colorectal cancer as compared to older age groups. People younger than 40 years are being diagnosed with relatively more advanced and aggressive disease. This study also identified smoking as a potential risk factor in younger adults.

Author Biographies

Sorath Bhutto, Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.

Resident physcian, deparment of medical oncology, Jinnah Post Gradute Medical Centre, Karachi

Sana Hashmat, Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.

Resident physician at department of medical oncology, JPMC, KARACHI

Ghulam Haider, Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.

Chief incharge, derpartment of oncology, jpmc, karachi

Abdul Rehman, Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.

resident physician at department of medical oncology, JPMC, KARACHI

Saima Zahoor, Department of Medical Oncology, Jinnah Post Graduate Medical Centre, Karachi.

senior registrar, medical onoclogy, JPMC, Karachi

Shayan Ali Qazi, Senior lecturer, Sindh Institute of Urology and Transplantation

Senior lecturer, SIUT, KARACHI

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Published

2024-12-31

How to Cite

Bhutto, S., Hashmat, S., Haider, G., Rehman, A., Zahoor, S., Qazi, S. A., & Qureshi, A. (2024). The Changing Trends Amongst Patients with Colorectal Carcinoma Presenting at Medical Oncology Department, JPMC. LIAQUAT MEDICAL RESEARCH JOURNAL, 6(4). https://doi.org/10.38106/LMRJ.2024.6.4-03