The assessment of aristida adscensionis and rumex hypogaeus comparative and combine antioxidant potential

Authors

  • Dr Fahim Ullah Khan Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Maria Niazi 1. Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Surayia Shahab Rani University Department of Pharmacy, University of Sargodha, Sargodha, Punjab, 40100, Pakistan
  • Khadija Khattak Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Khalid Wahab Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Zia UD Din Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Osama Alam Department of Biotechnology, University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Autif Hussain Mangi Institute of Biochemistry, University of Sindh Jamshoro, Sindh, Pakistan.
  • Muhammad Reyan Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Tariq Rahim Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Zakim Ullah Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan
  • Israr Ahmad Department of Zoology University of Science and Technology Bannu, Khyber, Pakhtunkhwa (28100), Pakistan

DOI:

https://doi.org/10.38106/LMRJ.2024.6.2-02

Keywords:

Aristida adscensionis, Rumex hypogaeus, Antioxidant activity

Abstract

Exogenous substances and cellular metabolism both produce free radicals in cells. The produced free radicals react with cell biomolecules, including DNA. The ensuing destruction of DNA, also known as oxidative DNA damage, which is connected to aging, carcinogenesis, and mutagenesis. The Aristida adscensionis plays an essential role in the modulation of free radicals. We examined the antioxidant therapy of individual or combined forms of the Aristida adscensionis and Rumex hypogaeus plant extracts. We noticed that Aristida adscensionis showed scavenging activity at various concentrations i.e. 50, 100, 250, 500, and 1000 ?g/ml was 42%, 50%, 62%, 69% and 75% respectively. The scavenging activity of Rumex hypogaeus at various concentrations was 43%, 52%, 58%, 66% and 75% against the standard of ascorbic acid. We noticed that the combined mixture of both plant extracts elucidated a significant antioxidant potential at different concentrations of 100 ?g/ml, 500 ?g/ml, and 1000 ?g/ml which were 58%, 70%, 74%, 81% and 86 %. Our research study demonstrates that combinaion of both plants' extract mixtures had a more substantial antioxidant capacity than each extract individually. This property of these plants can be used for cancer treatment, however further robust data is required.

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Published

2024-06-30

How to Cite

Dr Fahim Ullah Khan, Niazi, M., Surayia Shahab Rani, Khadija Khattak, Khalid Wahab, Zia UD Din, Osama Alam, Autif Hussain Mangi, Muhammad Reyan, Tariq Rahim, Zakim Ullah, & Israr Ahmad. (2024). The assessment of aristida adscensionis and rumex hypogaeus comparative and combine antioxidant potential . LIAQUAT MEDICAL RESEARCH JOURNAL, 6(2). https://doi.org/10.38106/LMRJ.2024.6.2-02

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