Involution of unilateral multicystic dysplastic kidney: Long term data from a single centre

Abstract

Unilateral multicystic dysplastic kidney (MCDK) is congenital anomaly which can be detected by ultrasound during antenatal period. The reported rate of MCDK ranges between 1 in 2,200 to 1 in 4,300 live births. This study was aimed to assess the determinants associated with the MCDK with follow-up until teens to evaluate the evolution of the disorder. This was an observational longitudinal study, involution degrees were observed following the baseline measurement of the size of the MCDK as documented on postnatal ultrasound, and long-term complications and renal function were also recorded.  A total of 350 patients were identified, while 90 patients fulfilled the criteria of the study and completed the study duration of 10 years. Out of which 19 (21.1%) patients reported involution of MCDK size during follow-up as complete and partial, 7 (7.7%) within first year of age, 5 (5.5%) during first 2 years and 7 (7.7%) within 4 years of age. Large-sized MCDK at the time of diagnosis is less likely to involute through the first decade of life. However, conventional treatment is rational with the absence of complications.